Bromide ion → N-(6-(2,4-dichlorophenyl)-5-(4-chlorophenyl)-3-cyanopyridin-2-yl)-N-isobutylpropionamide

HRID 832503

Reaction equation

HRID 832503 reaction equation
[Br-:58].[C:61]([CH2:62][CH3:63])(=[O:64])[Cl:65].[CH2:53]([NH2:54])[CH:55]([CH3:56])[CH3:57].[CH3:59][Mg+:60].[Cl:1][c:2]1[c:3](-[c:9]2[c:10](-[c:22]3[cH:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]3)[cH:11][c:12]([C:20]#[N:21])[c:13]([NH:15][CH2:16][CH:17]([CH3:18])[CH3:19])[n:14]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1.[Cl:29][c:30]1[c:31]([C:32]#[N:33])[cH:34][c:35](-[c:36]2[cH:37][cH:38][c:39]([Cl:40])[cH:41][cH:42]2)[c:43](-[c:44]2[cH:45][cH:46][c:47]([Cl:48])[cH:49][c:50]2[Cl:51])[n:52]1>>[Cl:1][c:2]1[c:3](-[c:9]2[c:10](-[c:22]3[cH:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]3)[cH:11][c:12]([C:20]#[N:21])[c:13]([N:15]([CH2:16][CH:17]([CH3:18])[CH3:19])[C:61]([CH2:62][CH3:63])=[O:64])[n:14]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

7

Reactant 6

HCID 259Bromide ionHCID 6558IsobutylamineHCID 62324Propionyl chlorideHCID 101506772-Chloro-5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)nicotinonitrileHCID 444409945-(4-Chlorophenyl)-6-(2,4-dichlorophenyl)-2-(isobutylamino)nicotinonitrileHCID 178477777HCID 178477777, compound

Product 1

HCID 68717477N-(6-(2,4-dichlorophenyl)-5-(4-chlorophenyl)-3-cyanopyridin-2-yl)-N-isobutylpropionamide

Sources & evidence

ORD record
ord-d939dbc2783f4e05859e0d5049bec6dc
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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