Acetonitrile → Methyl 3-amino-6-bromo-5-fluoro-2-methylbenzoate

Reaction equation

[Br:14][N:15]1[C:16](=[O:17])[CH2:18][CH2:19][C:20]1=[O:21].[CH3:22][C:23]#[N:24].[NH2:1][c:2]1[c:3]([CH3:13])[c:4]([C:5](=[O:6])[O:7][CH3:8])[cH:9][c:10]([F:12])[cH:11]1>>[NH2:1][c:2]1[c:3]([CH3:13])[c:4]([C:5](=[O:6])[O:7][CH3:8])[c:9]([Br:14])[c:10]([F:12])[cH:11]1

Participants

Reactant 3

HCID 6342Acetonitrile

HCID 67184N-bromobutanimide

HCID 53419617Methyl 3-amino-5-fluoro-2-methylbenzoate

Product 1

HCID 59145869Methyl 3-amino-6-bromo-5-fluoro-2-methylbenzoate

Sources & evidence

ORD record: ord-3f4b61f1998c49c1bdc9aaf2d025a68b
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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