Formic Acid → N-[3-(4-chlorophenyl)-3-(4-fluorophenyl)prop-2-enyl]pipecolic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([CH:4]1[N:5]([CH2:10][CH2:11][C:12]([OH:13])([c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[c:21]2[cH:22][cH:23][c:24]([Cl:27])[cH:25][cH:26]2)[CH2:6][CH2:7][CH2:8][CH2:9]1)=[O:28].[CH:29]([OH:30])=[O:31]>>[CH3:1][O:2][C:3]([CH:4]1[N:5]([CH2:10][CH:11]=[C:12]([c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[c:21]2[cH:22][cH:23][c:24]([Cl:27])[cH:25][cH:26]2)[CH2:6][CH2:7][CH2:8][CH2:9]1)=[O:28]Participants
3
Sources & evidence
- ORD record
- ord-d563af3da5be4c8da1e83ffa5f3a703f
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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