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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 833544Generated: October 26, 2026

Dichloromethane → trans-4-(4-(methylamino)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-ylamino)-N-(2-(trifluoromethyl)benzyl)cyclohexanecarboxamide

https://huagongshe.com/reaction/833544

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
Reactant4-(Dimethylamino)pyridineHCID 14284—
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactanttrans-4-(4-(Methylamino)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-ylamino)cyclohexanecarboxylic acidHCID 67330775—
Producttrans-4-(4-(methylamino)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-ylamino)-N-(2-(trifluoromethyl)benzyl)cyclohexanecarboxamideHCID 25117871—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-82eba2d2dbf54e8a91d8c910bb3921b6
Source noteTest data from https://doi.org/10.1039/C8SC04228D