Methanol → N-(4-Fluorobenzyl)-2,2,4,6,7-pentamethyl-3-phenyl-2,3-dihydro-1-benzofuran-5-amine

Reaction equation

[CH3:31][OH:32].[F:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[c:10]([CH3:28])[c:11]([CH3:27])[c:12]3[c:13]([c:25]2[CH3:26])[CH:14]([c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[C:15]([CH3:17])([CH3:18])[O:16]3)[cH:29][cH:30]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:8][c:9]2[c:10]([CH3:28])[c:11]([CH3:27])[c:12]3[c:13]([c:25]2[CH3:26])[CH:14]([c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[C:15]([CH3:17])([CH3:18])[O:16]3)[cH:29][cH:30]1

Participants

Reactant 2

HCID 887Methanol

HCID 102945904-Fluoro-N-(2,2,4,6,7-pentamethyl-3-phenyl-2,3-dihydro-1-benzofuran-5-yl)benzamide

Product 1

HCID 9886670N-(4-Fluorobenzyl)-2,2,4,6,7-pentamethyl-3-phenyl-2,3-dihydro-1-benzofuran-5-amine

Sources & evidence

ORD record: ord-14cf1d14f9d2448db231b145df64da73
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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