HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfoxide → 4-(2-Amino-4-methoxy-benzothiazol-7-yl)-1-methyl-piperazin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Acetic Acid Mixture with Hydrobromic Acid | HCID 21893785 | — |
| Reactant | [2-Methoxy-5-(4-methyl-3-oxo-piperazin-1-yl)-phenyl]-thiourea | HCID 22015742 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4-(2-Amino-4-methoxy-benzothiazol-7-yl)-1-methyl-piperazin-2-one | HCID 22015741 | — |
Reaction Steps
From [2-methoxy-5-(4-methyl-3-oxo-piperazin-1-yl)-phenyl]-thiourea with HBr—AcOH (4 equiv.) and DMSO (2.4 equiv.) in AcOH. ES-MS m/e (%): 293 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087761B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-d179064351194b43a86982c843ec674b |
| Source note | uspto-grants-2006_08 |