Dimethyl Sulfoxide → 3,4-dihydro-2,2-dimethyl-3,4-epoxy-2H-pyrano[3,2-c]pyridine

Reaction equation

[CH3:17][S:18]([CH3:19])=[O:20].[CH3:3][C:4]1([CH3:16])[O:5][c:6]2[cH:7][cH:8][n:9][cH:10][c:11]2[CH:12]([OH:15])[CH:13]1[Br:14].[H-:2].[Na+:1]>>[CH3:3][C:4]1([CH3:16])[O:5][c:6]2[cH:7][cH:8][n:9][cH:10][c:11]2[CH:12]2[CH:13]1[O:15]2

Participants

Reactant 4

HCID 679Dimethyl Sulfoxide

HCID 923Sodium Ion

HCID 166653Hydride

HCID 147434603-Bromo-2,2-dimethyl-3,4-dihydropyrano[3,2-c]pyridin-4-ol

Product 1

HCID 108560303,4-dihydro-2,2-dimethyl-3,4-epoxy-2H-pyrano[3,2-c]pyridine

Sources & evidence

ORD record: ord-885ea38642c34724bcfa681113a0a807
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…