4-Bromo-1-methylpyridin-2(1H)-one → 2,2-Dimethyl-3-[3-[1-[4-(1-methyl-2-oxo-4-pyridinyl)phenyl]ethyl]-2-oxo-6-phenyl-1,3-oxazinan-6-yl]propanenitrile
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH3:9])[N:10]2[C:11](=[O:28])[O:12][C:13]([c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)([CH2:22][C:23]([C:24]#[N:25])([CH3:26])[CH3:27])[CH2:14][CH2:15]2)[cH:6][cH:7]1.[Br:29][c:30]1[cH:31][c:32](=[O:37])[n:33]([CH3:36])[cH:34][cH:35]1>>[c:2]1(-[c:30]2[cH:31][c:32](=[O:37])[n:33]([CH3:36])[cH:34][cH:35]2)[cH:3][cH:4][c:5]([CH:8]([CH3:9])[N:10]2[C:11](=[O:28])[O:12][C:13]([c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)([CH2:22][C:23]([C:24]#[N:25])([CH3:26])[CH3:27])[CH2:14][CH2:15]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-95193317c21243fe98e7948ca1c3181e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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