5-Chloro-1-benzofuran → (RS)-2-[1-(5-Chloro-benzofuran-2-yl)-methanoyl]-4-methyl-piperazine-1-carboxylic acid tert-butyl ester

HRID 836093

Reaction equation

HRID 836093 reaction equation
[CH3:1][C:2]([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:15]([N:16]([O:17][CH3:18])[CH3:19])=[O:20])[CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]1.[Cl:21][c:22]1[cH:23][cH:24][c:25]2[c:26]([cH:27][cH:28][o:29]2)[cH:30]1>>[CH3:1][C:2]([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:15](=[O:20])[c:28]2[cH:27][c:26]3[c:25]([cH:24][cH:23][c:22]([Cl:21])[cH:30]3)[o:29]2)[CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 900135-Chloro-1-benzofuranHCID 86625772(RS)-2-(methoxy-methyl-carbamoyl)4-methyl-piperazine-1-carboxylic acid dimethyl-ethyl ester

Product 1

HCID 66967838(RS)-2-[1-(5-Chloro-benzofuran-2-yl)-methanoyl]-4-methyl-piperazine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-1d9ce88798e74c1ab30a1b805c7ed749
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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