(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)methanone → 4-[4-Amino-5-(3-amino-benzoyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-piperidine-1-carboxylic acid tert-butyl ester

HRID 837293

Reaction equation

HRID 837293 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([n:12]2[c:13]3[n:14][cH:15][n:16][c:17]([Cl:18])[c:19]3[cH:20][cH:21]2)[CH2:22][CH2:23]1.[NH2:24][c:25]1[c:26]2[c:27]([n:28][cH:29][n:30]1)[n:31]([CH:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1)[cH:32][c:33]2[C:34](=[O:35])[c:36]1[cH:37][c:38]([NH2:42])[cH:39][cH:40][cH:41]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:45][CH2:44][CH:43]([n:31]2[c:27]3[c:26]([c:25]([NH2:24])[n:30][cH:29][n:28]3)[c:33]([C:34](=[O:35])[c:36]3[cH:37][c:38]([NH2:42])[cH:39][cH:40][cH:41]3)[cH:32]2)[CH2:47][CH2:46]1

Participants

3

Reactant 2

HCID 11859044(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)methanoneHCID 58270310tert-butyl 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)piperidine-1-carboxylate

Product 1

HCID 672197434-[4-Amino-5-(3-amino-benzoyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-609f7fae5e1a48a18ec38c596dd9139b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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