2-Thiophenesulfonyl chloride → 5-methyl-N-[6-(2-(2-thiophenesulfonylamino)-ethoxy)-5-(o-methoxyphenoxy)-2-(4-pyridyl)-4-pyrimidinyl]-2-pyridine sulfonamide

HRID 837295

Reaction equation

HRID 837295 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[NH:11][c:12]2[n:13][c:14](-[c:31]3[cH:32][cH:33][n:34][cH:35][cH:36]3)[n:15][c:16]([O:27][CH2:28][CH2:29][NH2:30])[c:17]2[O:18][c:19]2[c:20]([O:25][CH3:26])[cH:21][cH:22][cH:23][cH:24]2)[n:6][cH:7]1.[s:37]1[c:38]([S:42](=[O:43])(=[O:44])[Cl:45])[cH:39][cH:40][cH:41]1>>[CH3:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[NH:11][c:12]2[n:13][c:14](-[c:31]3[cH:32][cH:33][n:34][cH:35][cH:36]3)[n:15][c:16]([O:27][CH2:28][CH2:29][NH:30][S:42]([c:38]3[s:37][cH:41][cH:40][cH:39]3)(=[O:43])=[O:44])[c:17]2[O:18][c:19]2[c:20]([O:25][CH3:26])[cH:21][cH:22][cH:23][cH:24]2)[n:6][cH:7]1

Participants

3

Reactant 2

HCID 855182-Thiophenesulfonyl chlorideHCID 181842545-methyl-N-[6-(2-aminoethoxy)-5-(o-methoxyphenoxy)-2-(4-pyridyl)-4-pyrimidinyl]-2-pyridine sulfonamide

Product 1

HCID 181841795-methyl-N-[6-(2-(2-thiophenesulfonylamino)-ethoxy)-5-(o-methoxyphenoxy)-2-(4-pyridyl)-4-pyrimidinyl]-2-pyridine sulfonamide

Sources & evidence

ORD record
ord-56aeb440371f4213903b5399e7a7b94a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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