Bicarbonate Ion → N-(2,6-dichloropyrimidin-4-yl)acetamide

HRID 837337Notes

Reaction equation

[CH3:15][C:16](=[O:17])[O:18][C:19](=[O:20])[CH3:21].[NH2:1][c:2]1[n:3][c:4]([Cl:9])[n:5][c:6]([Cl:8])[cH:7]1.[Na+:14].[O-:10][C:11]([OH:12])=[O:13]>>[NH:1]([c:2]1[n:3][c:4]([Cl:9])[n:5][c:6]([Cl:8])[cH:7]1)[C:16]([CH3:15])=[O:17]

Participants

Reactant 4

HCID 769Bicarbonate Ion

HCID 923Sodium ion

HCID 7918Acetic Anhydride

HCID 823874-Pyrimidinamine, 2,6-dichloro-

Product 1

HCID 4713752N-(2,6-dichloropyrimidin-4-yl)acetamide

Sources & evidence

ORD record: ord-21825ee6cd1b4d75bc981427c5103f2f
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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