Isobutyric anhydride → HCID 20322014, compound
Reaction equation
CC1C=C2C=CC=CN2N=1.C(OC(=O)C(C)C)(=O)C(C)C.[C:22]([C:27]1[C:28]([CH3:36])=[N:29][N:30]2[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=12)(=O)[CH:23]([CH3:25])[CH3:24]>S(=O)(=O)(O)O>[CH2:22]([C:27]1[C:28]([CH3:36])=[N:29][N:30]2[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=12)[CH:23]([CH3:25])[CH3:24]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
2-Methylpyrazolo[1,5-a]pyridine was worked up according to the same process as shown in example 1, with an excess isobutyric anhydride in the presence of 2-3 drops of concentrated sulfuric acid to prepare 3-isobutyryl-2-methylpyrazolo[1,5-a]pyridine (139-140°/5 mmHg). Yield 40%.
Sources & evidence
- ORD record
- ord-63f70b4ee1244ea0ace67cf5731b45cc
- Source dataset
- uspto-grants-1978_06
- Patent number
- US04097483
Reaction notes
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