Methanol, 1,1-diethoxy-, 1-acetate → HCID 54399738, compound

Reaction equation

[Cl:1][C:2]1[N:7]=[C:6]2[NH:8][C:9](=[O:11])[CH2:10][C:5]2=[CH:4][CH:3]=1.[C:12]([O:15][CH:16](OCC)OCC)(=O)[CH3:13]>>[Cl:1][C:2]1[N:7]=[C:6]2[NH:8][C:9](=[O:11])[C:10](=[CH:16][O:15][CH2:12][CH3:13])[C:5]2=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 84166Methanol, 1,1-diethoxy-, 1-acetate

HCID 219070476-Chloro-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

Product 1

HCID 54399738HCID 54399738, compound

Procedure

This compound was synthesized from 6-chloro-1H-pyrrolo[2,3-b]pyridin-2-one and diethoxymethyl acetate according to Procedure A. 1H NMR 400 MHz (DMSO-d6): δ11.06 (s, 1H); 7.84 (s, 1H); 7.63 (d, 1H); 6.98 (d, 1H); 4.39 (m, 2H); 1.32 (m, 3H).

Sources & evidence

ORD record: ord-c2f4194ba675491bb5af301c4f017489
Source dataset: uspto-grants-2002_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06369086B1

Reaction notes

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