HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethinylestradiol → Norgestimate and Ethinyl Estradiol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethinylestradiol | HCID 5991 | — |
| Reactant | Norgestimate | HCID 6540478 | — |
| Product | Norgestimate and Ethinyl Estradiol | HCID 9571023 | — |
Reaction Steps
PEG 8000 is micronized by Jet mill together with ethinyl estradiol at the ratio of ethinyl estradiol to PEG from 1:1 to 1:60. Adjust Jet mill to produce particle size of 5-10 μm. Norgestimate is micronized separately to particle size of 5-15 μm. Micronized norgestimate powder is electrically charged, and deposited on the substrate surface. Micronized PEG 8000/ethinyl estradiol mixture is triboelectrically charged, and deposited on top of norgestimate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06372246B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-e1ccff6b9e654b2d9c440793599b1e6d |
| Source note | uspto-grants-2002_04 |