5-(3-Tert-butoxycarbonylaminopropyl)-tetrahydrofuran-2-carboxylic acid methyl ester → 5-(3-Amino-propyl)-tetrahydrofuran-2-carboxylic acid methyl ester hydrochloride salt
Reaction equation
[CH3:1][O:2][C:3]([CH:5]1[CH2:9][CH2:8][CH:7]([CH2:10][CH2:11][CH2:12][NH:13]C(OC(C)(C)C)=O)[O:6]1)=[O:4].[ClH:21].COC(C1OC(CCCN)=CC=1)=O>>[ClH:21].[CH3:1][O:2][C:3]([CH:5]1[CH2:9][CH2:8][CH:7]([CH2:10][CH2:11][CH2:12][NH2:13])[O:6]1)=[O:4]Participants
3
Procedure
The title compound was prepared from 5-(3-tert-butoxycarbonylamino-propyl)-tetrahydrofuran-2-carboxylic acid methyl ester following the procedure described in Step C for Preparation 2a.
Sources & evidence
- ORD record
- ord-7a743d12dee9447481e506fb70915d32
- Source dataset
- uspto-grants-2002_04
- Patent number
- US06376502B1
Reaction notes
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