HCID 178478098, compound → HCID 178420213, compound
Reaction equation
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[C:4](Cl)[C:3]=1[CH2:9][C:10]1[NH:14][N:13]=[N:12][N:11]=1>[Pd].CO>[C:3]1([CH2:9][C:10]2[NH:14][N:13]=[N:12][N:11]=2)[CH:2]=[CH:7][CH:6]=[CH:5][CH:4]=1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
The mixture of 5-(2,6-dichlorophenylmethyl)tetrazole (355 mg), 5% palladium on activated carbon (93 mg) and methanol (8 ml) was stirred for 1 h room temperature under an atmosphere of hydrogen gas. The reaction mixture was filtered through Celite (trade mark) and the filtrate was concentrated to give the title compound having the following physical data.
Workup
- filtrationThe reaction mixture was filtered through Celite (trade mark)
- concentrationthe filtrate was concentrated
Sources & evidence
- ORD record
- ord-dbca2720337a4c9a98eaadeb62c55c46
- Source dataset
- uspto-grants-2002_04
- Patent number
- US06376484B1
Reaction notes
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