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Ethanol → HCID 22611021, compound

HRID 843579
Notes
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Reaction equation

HRID 843579 reaction equation
[N+:1]([C:4]1[CH:22]=[CH:21][CH:20]=[CH:19][C:5]=1[NH:6][C:7]1[CH:12]=[CH:11][C:10]([NH:13][C:14]2[S:15][CH:16]=[CH:17][N:18]=2)=[CH:9][CH:8]=1)([O-])=O.O.O.O.O.O.O.O.O.O.[S-2].[Na+].[Na+].[Cl-].[NH4+].C(O)C>O>[NH2:1][C:4]1[CH:22]=[CH:21][CH:20]=[CH:19][C:5]=1[NH:6][C:7]1[CH:12]=[CH:11][C:10]([NH:13][C:14]2[S:15][CH:16]=[CH:17][N:18]=2)=[CH:9][CH:8]=1
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

6

Reactant 4

HCID 702EthanolHCID 25517Ammonium ChlorideHCID 73972Sodium sulfide nonahydrateHCID 18522031HCID 18522031, compound

Product 1

HCID 22611021HCID 22611021, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 2-nitro-N-(4-(2-thiazolylamino)phenyl)aniline (1.2 g, 3.8 mmol), sodium sulfide nona hydrate (4.61, 19.2 mmol), ammonium chloride (1.03 g, 19.2 mmol) and ethanol (40 ml) was stirred at reflux for 40 h. Water (50 ml) was added, the mixture was stirred and filtered. Yield 0.49 g, 46%. M.p. 184-186° C.

Workup

  1. temperatureat reflux for 40 h
  2. stirringthe mixture was stirred
  3. filtrationfiltered

Sources & evidence

ORD record
ord-77b70694d4454326bbc879310c4c3b91
Source dataset
uspto-grants-2002_04
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US06380180B1

Reaction notes

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On this pageParticipantsProcedureWorkupSources & evidenceReaction notes