Thionyl Chloride → 4-Cyclohexylbutanoyl chloride

HRID 844417

Reaction equation

HRID 844417 reaction equation
[CH2:1]1[CH2:6][CH2:5][CH:4]([CH2:7][CH2:8][CH2:9][C:10]([OH:12])=O)[CH2:3][CH2:2]1.S(Cl)([Cl:15])=O>>[CH:4]1([CH2:7][CH2:8][CH2:9][C:10]([Cl:15])=[O:12])[CH2:5][CH2:6][CH2:1][CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 75200Cyclohexanebutanoic acid

Product 1

HCID 133156254-Cyclohexylbutanoyl chloride

Procedure

50 g of 4-cyclohexanebutyric acid are refluxed for 4 hours in 160 ml of thionyl chloride. After evaporation of the excess thionyl chloride, the expected product is distilled off. b.p.=70-80° C. at 400 Pa.

Workup

  1. customAfter evaporation of the excess thionyl chloride
  2. distillationthe expected product is distilled off

Sources & evidence

ORD record
ord-b67d361baaf844d68daab285fd9d6e54
Source dataset
uspto-grants-2002_04
Patent number
US06380230B1

Linked notes

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