2-(2-Methylethyl)-6-methylbenzoic acid → HCID 69336578, compound

HRID 844853

Reaction equation

HRID 844853 reaction equation
C[O:2][C:3](=[O:24])[C@H:4]([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[C:14](=[O:23])[N:15]([CH3:22])[C:16](=[O:21])[N:17]([CH3:20])[C:18]=2[CH3:19])=[CH:9][CH:8]=1)[NH2:5].[CH3:25][CH2:26][CH2:27][C:28]1[CH:36]=[CH:35][CH:34]=[C:33]([CH3:37])[C:29]=1[C:30](O)=[O:31]>>[CH3:25][CH2:26][CH2:27][C:28]1[CH:36]=[CH:35][CH:34]=[C:33]([CH3:37])[C:29]=1[C:30]([NH:5][C@H:4]([C:3]([OH:2])=[O:24])[CH2:6][C:7]1[CH:8]=[CH:9][C:10]([C:13]2[C:14](=[O:23])[N:15]([CH3:22])[C:16](=[O:21])[N:17]([CH3:20])[C:18]=2[CH3:19])=[CH:11][CH:12]=1)=[O:31]

Participants

3

Reactant 2

HCID 226137482-(2-Methylethyl)-6-methylbenzoic acidHCID 693369754-(1,3,6-trimethyl-2,4-dioxo-5-pyrimidinyl)-L-phenylalanine methyl ester

Product 1

HCID 69336578HCID 69336578, compound

Procedure

N-[[2-(2-methylethyl)-6-methylphenyl]carbonyl]-4-(1,3,6-trimethyl-2,4-dioxo-5-pyrimidinyl)-L-phenylalanine was prepared from 4-(1,3,6-trimethyl-2,4-dioxo-5-pyrimidinyl)-L-phenylalanine methyl ester and 2-(2-methylethyl)-6-methylbenzoic acid using the general procedures described in example 7 and was obtained as an amorphous white solid. ES-HRMS m/e calcd for C27H31N3O5 (M+Na) 500.2156, found 500.2160.

Workup

  1. customwas obtained as an amorphous white solid

Sources & evidence

ORD record
ord-c92b869201b54800aba333425698294b
Source dataset
uspto-grants-2002_04
Patent number
US06380387B1

Linked notes

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