2-Aminomethyl-2-octadecylcarbamoyloxymethyltetrahydrofuran → 2-(3-Chloropropylsulfonylaminomethyl)-2-octadecylcarbamoyloxymethyltetrahydrofuran
Reaction equation
[NH2:1][CH2:2][C:3]1([CH2:8][O:9][C:10](=[O:30])[NH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[CH2:7][CH2:6][CH2:5][O:4]1.[Cl:31][CH2:32][CH2:33][CH2:34][S:35](NCC(OC)CSCCCCCCCCCCCCCCCC)(=[O:37])=[O:36]>>[Cl:31][CH2:32][CH2:33][CH2:34][S:35]([NH:1][CH2:2][C:3]1([CH2:8][O:9][C:10](=[O:30])[NH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[CH2:7][CH2:6][CH2:5][O:4]1)(=[O:37])=[O:36]Participants
3
Procedure
2-Aminomethyl-2-octadecylcarbamoyloxymethyltetrahydrofuran IV b2 is allowed to react and worked by the same procedure as described in (4). The summary of the experimental condition and the physical data of the product are listed in the Table 7.
Workup
- customto react