HCID 54084144, compound → HCID 18800733, compound
Reaction equation
[C:1]1([CH:7]=[CH:8][CH2:9][CH:10]2[NH:16][C:15](=[O:17])[CH2:14][CH2:13][CH2:12][CH2:11]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>CO.[Pd]>[C:1]1([CH2:7][CH2:8][CH2:9][CH:10]2[NH:16][C:15](=[O:17])[CH2:14][CH2:13][CH2:12][CH2:11]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
The title material of Example 32 (0.46 g, 2.0 mmol) in MeOH and 4% Pd on carbon (0.10 g) were combined in a standard Parr apparatus (125 mL bottle). The hydrogenation was carried out at room temperature under a H2 pressure of 5 psi for 1 hr. All solvent was then removed under reduced pressure to yield 0.50 (09%) of the title material as a white semi-solid.
Workup
- customwas carried out at room temperature under a H2
- customfor 1 hr
- customAll solvent was then removed under reduced pressure
Sources & evidence
- ORD record
- ord-f0a888963ef647c2b390f93c16c48191
- Source dataset
- uspto-grants-2000_01
- Patent number
- US06011028
Reaction notes
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