4-Chloro-alpha,alpha,alpha-trifluoro-3-nitrotoluene → 2-Nitro-4-trifluoromethylanisole

HRID 851344

Reaction equation

Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[CH3:15][O-:16].[Na+]>>[CH3:15][O:16][C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13]

Participants

Reactant 2

HCID 84624-Chloro-alpha,alpha,alpha-trifluoro-3-nitrotoluene

HCID 10942334Sodium Methoxide

Product 1

HCID 967482-Nitro-4-trifluoromethylanisole

Procedure

Reaction of 4-chloro-3-nitrobenzotrifluoride with sodium methoxide to give 4-methoxy-3-nitro-benzotrifluoride

Sources & evidence

ORD record: ord-b0d897d6a5c94e008a81dd24b0db9a23
Source dataset: uspto-grants-1983_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04384135

Linked notes

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