HCID 131712999, compound → (3S)-3-Amino-2-oxoazetidine-1-sulfonic acid
Reaction equation
C([N+](CCCC)(CCCC)CCCC)CCC.C(OC([NH:25][C@H:26]1[CH2:29][N:28]([S:30]([O-:33])(=[O:32])=[O:31])[C:27]1=[O:34])=O)(C)(C)C>C(O)=O.C(Cl)Cl>[NH2:25][C@H:26]1[CH2:29][N:28]([S:30]([OH:33])(=[O:32])=[O:31])[C:27]1=[O:34]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
(S)-3-[(t-Butoxycarbonyl)amino]-2-oxo-1-azetidinesulfonic acid, tetra-n-butylammonium salt (3.06 g) is dissolved in 18 ml of 97% formic acid, stirred for 4 hours, diluted with methylene chloride, filtered, washed and dried to give 0.52 g of the title compound; melting point 208°-210° C., dec.; [α]D21 =-39.9[c=2, water].
Workup
- filtrationfiltered
- washwashed
- customdried
Sources & evidence
- ORD record
- ord-5f106eb708aa413abdde6e2582db6fe2
- Source dataset
- uspto-grants-1983_05
- Patent number
- US04386034
Reaction notes
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