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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 854629Generated: October 27, 2026

3-Methylbenzaldehyde → 4-Iodomethyl-5-methyl-2-m-tolyloxazole

https://huagongshe.com/reaction/854629

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethylbenzaldehydeHCID 12105—
Reactant2,3-Butanedione monoximeHCID 6409633—
Reactant4-Iodomethyl-5-phenyl-2-p-tolyloxazoleHCID 57434504—
Product4-Iodomethyl-5-methyl-2-m-tolyloxazoleHCID 21980308—

Reaction Steps

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, diacetylmonoxime and m-tolualdehyde gave 4-iodomethyl-5-methyl-2-m-tolyloxazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07259177B2
Source datasetuspto-grants-2007_08
ORD IDord-ee97f07850b04a52a753f40cdc3c2c2e
Source noteuspto-grants-2007_08