HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenethylamine, m-trifluoromethyl- → HCID 69342790, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenethylamine, m-trifluoromethyl- | HCID 104223 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | (4-Cyclopropylbenzyl)-[2-(4-fluoro-3-trifluoromethylphenyl)-ethyl]-amine | HCID 69342889 | — |
| Reactant | 4-(1-Methoxycyclopropyl)-benzaldehyde | HCID 86093727 | — |
| Product | HCID 69342790 | HCID 69342790 | — |
Reaction Steps
The title compound was synthesized in analogy to (4-cyclopropylbenzyl)-[2-(4-fluoro-3-trifluoromethylphenyl)-ethyl]-amine (described in example S53) using 4-(1-methoxy-cyclopropyl)-benzaldehyde (105 mg, 0.60 mmol), 2-(3-trifluoromethylphenyl)-ethylamine (113 mg, 0.60 mmol) and sodium borohydride (34 mg, 0.89 mmol). The desired product was isolated without further purification as a colorless oil. MS (ISP) 350.4 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07259183B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-265f379c2c0b448885da0caac7c72715 |
| Source note | uspto-grants-2007_08 |