HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Piperidin-1-yl)acetic acid hydrochloride → HCID 68358088, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Piperidin-1-yl)acetic acid hydrochloride | HCID 201096 | — |
| Reactant | methyl 4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-amino-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)benzoate | HCID 68357865 | — |
| Product | HCID 68358088 | HCID 68358088 | — |
Reaction Steps
The title compound was prepared from methyl 4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-amino-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)benzoate following the general procedure described for the parallel synthesis of C-17 amides above, using piperidin-1-ylacetic acid hydrochloride as the reacting carboxylic acid. LCMS: m/e 655.7 (M+H)+, 4.68 min (method 3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846647B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-d8a4c55f5c2b455eba91048c01a0c8fc |
| Source note | uspto-grants-2014_09 |