Pyridine → N-[3-(4,4-dimethyl-6-trifluoromethyl-1,2,3,4-tetrahydro-quinolin-2-yl)-phenyl]-2-fluoro-benzenesulfonamide

HRID 85972

Reaction equation

HRID 85972 reaction equation
[CH3:1][C:2]1([CH3:23])[CH2:3][CH:4]([c:16]2[cH:17][c:18]([NH2:22])[cH:19][cH:20][cH:21]2)[NH:5][c:6]2[cH:7][cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[cH:10][c:11]21.[Cl:41][CH2:42][Cl:43].[F:30][c:31]1[c:32]([S:37](=[O:38])(=[O:39])[Cl:40])[cH:33][cH:34][cH:35][cH:36]1.[cH:24]1[cH:25][cH:26][n:27][cH:28][cH:29]1>>[CH3:1][C:2]1([CH3:23])[CH2:3][CH:4]([c:16]2[cH:17][c:18]([NH:22][S:37]([c:32]3[c:31]([F:30])[cH:36][cH:35][cH:34][cH:33]3)(=[O:38])=[O:39])[cH:19][cH:20][cH:21]2)[NH:5][c:6]2[cH:7][cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[cH:10][c:11]21

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 1377612-Fluorobenzenesulphonyl chlorideHCID 672916153-(4,4-Dimethyl-6-trifluoromethyl-1,2,3,4-tetrahydro-quinolin-2-yl)-phenylamine

Product 1

HCID 56966129N-[3-(4,4-dimethyl-6-trifluoromethyl-1,2,3,4-tetrahydro-quinolin-2-yl)-phenyl]-2-fluoro-benzenesulfonamide

Sources & evidence

ORD record
ord-49dbec4bde364a69aa71dfac00adaf47
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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