Ethanol → HCID 22097137, compound
Reaction equation
[CH2:1]([N:3]1[C:12]2[C:7](=[CH:8][C:9]([NH:16]C(=O)C(OCC)=O)=[C:10]([N+:13]([O-:15])=[O:14])[CH:11]=2)[NH:6][C:5](=[O:24])[C:4]1=[O:25])[CH3:2].O.C(O)C>S(=O)(=O)(O)O>[NH2:16][C:9]1[CH:8]=[C:7]2[C:12](=[CH:11][C:10]=1[N+:13]([O-:15])=[O:14])[N:3]([CH2:1][CH3:2])[C:4](=[O:25])[C:5](=[O:24])[NH:6]2Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
24 g (68.6 mmol) of this amide were refluxed in a mixture of 13 ml of concentrated sulfuric acid, 240 ml of water and 250 ml of ethanol for 3 h. The precipitate was then filtered off with suction to yield 16.2 g (98%) of the product.
Workup
- filtrationThe precipitate was then filtered off with suction
Sources & evidence
- ORD record
- ord-fdade74b5df2442bad1751f04d0fd28e
- Source dataset
- uspto-grants-1998_02
- Patent number
- US05714489
Reaction notes
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