Methanol → 3,5-Bis(trifluoromethyl)benzylamine

HRID 86159

Reaction equation

[CH3:17][OH:18].[F:1][C:2]([c:3]1[cH:4][c:5]([C:6]#[N:7])[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1)([F:15])[F:16].[H:19][H:20].[Pd:21]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][NH2:7])[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1)([F:15])[F:16]

Participants

Reactant 4

HCID 887Methanol

HCID 23938Palladium

HCID 967463,5-Bis(trifluoromethyl)benzonitrile

HCID 178418361HCID 178418361, compound

Product 1

HCID 5210993,5-Bis(trifluoromethyl)benzylamine

Sources & evidence

ORD record: ord-e47e0a260925488c8dfd39eae38e0644
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Linked notes

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