HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Bromide → 2-Ethoxybenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Bromide | HCID 6332 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Hydroxybenzonitrile | HCID 11907 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 2-Ethoxybenzonitrile | HCID 576922 | 97.1% |
Reaction Steps
25 g (210 mmol) of 2-hydroxylbenzonitrile are heated, together with 87 g of potassium carbonate and 34.3 g (314.8 mmol) of ethyl bromide, in 500 ml of acetone under reflux overnight. The solid is filtered off, the solvent is removed in vacuo and the residue is distilled in vacuo. 30.0 g (97%) of a colorless liquid are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091203B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-ce3fd0b48b39417c9f1ac902d61127bf |
| Source note | uspto-grants-2006_08 |