Methyl 3-methoxybenzoate → 2-(3-Methoxyphenyl)-2-propanamine
Reaction equation
CO[C:3]1[CH:8]=[CH:7][C:6]([C:9]([NH2:12])([CH3:11])[CH3:10])=[CH:5][CH:4]=1.[CH3:13][O:14]C1C=C(C=CC=1)C(OC)=O>>[CH3:13][O:14][C:8]1[CH:7]=[C:6]([C:9]([NH2:12])([CH3:10])[CH3:11])[CH:5]=[CH:4][CH:3]=1Participants
3
Procedure
Following a procedure similar to that described in Preparation 10a, but using methyl 3-methoxybenzoate as a starting material, in a relative amount similar to that used in that Preparation, the title compound was obtained in a yield of 31%.
Workup
- customin a relative amount similar to that used in that Preparation
Sources & evidence
- ORD record
- ord-7c8c1e4e5ff240e1a19dfe1583179a0c
- Source dataset
- uspto-grants-1998_02
- Patent number
- US05717088
Reaction notes
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