3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride) → US8865911, 46b Isomer 2

HRID 86235

Reaction equation

HRID 86235 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([cH:6][cH:7]1)[O:8][C:9]1([CH2:10][C:11]23[N:12]=[C:13]([CH3:17])[C:14]([NH2:16])=[N:15]3)[CH2:18][O:19][CH2:20][CH2:21][CH2:22]1.[Cl:23][c:24]1[cH:25][c:26]([B:31]([OH:32])[OH:33])[cH:27][cH:28][c:29]1[F:30]>>[c:2]1(-[c:26]2[cH:25][c:24]([Cl:23])[c:29]([F:30])[cH:28][cH:27]2)[cH:3][c:4]2[c:5]([cH:6][cH:7]1)[O:8][C:9]1([CH2:10][C:11]23[N:12]=[C:13]([CH3:17])[C:14]([NH2:16])=[N:15]3)[CH2:18][O:19][CH2:20][CH2:21][CH2:22]1

Participants

3

Reactant 2

HCID 27346603-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride)HCID 573861526'-Bromo-5-methyl-5'',6''-dihydro-4''H-dispiro[imidazole-2,4'-chromene-2',3''-pyran]-4-amine

Product 1

HCID 57386154US8865911, 46b Isomer 2

Sources & evidence

ORD record
ord-d140c5ccc58a46e6929e00a14feda63d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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