Chloroform → HCID 2797868, compound
Reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH:7](O)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:3][CH:2]=1.C(Cl)(Cl)[Cl:16].O=S(Cl)[Cl:21]>C(Cl)Cl>[ClH:16].[N:1]1[CH:6]=[CH:5][C:4]([CH:7]([Cl:21])[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:3][CH:2]=1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
To a solution of 27.75 g (0.15 mol) of (4-pyridyl)benzyl alcohol and 200 ml of chloroform is run in dropwise, at room temperature, a solution of 15.25 ml (0.2 mol) of SOCl2 and 50 ml of CH2Cl2.
Workup
- customat room temperature
Sources & evidence
- ORD record
- ord-d10fc50f700d493ab1ed685d939c5f84
- Source dataset
- uspto-grants-1998_02
- Patent number
- US05719168
Reaction notes
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