Ammonia → (4-Phenylpyrrolidin-3-yl)methanol

Reaction equation

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([CH2:19][OH:20])[CH:11]([c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:12]1.[CH3:26][CH2:27][OH:28].[CH3:29][OH:30].[CH:21]([O-:22])=[O:23].[NH3:25].[NH4+:24].[OH-:31].[OH-:33].[Pd+2:32]>>[NH:8]1[CH2:9][CH:10]([CH2:19][OH:20])[CH:11]([c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:12]1

Participants

Reactant 8

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 219127561-Benzyl-4-phenyl-3-pyrrolidinemethanol

Product 1

HCID 13316928(4-Phenylpyrrolidin-3-yl)methanol

Sources & evidence

ORD record: ord-7c43f00e90b54b529d08c1a5d86f10d9
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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