2-(Dimethylamino)ethanol → Isopropyl 2-dimethylaminoethyl carbonate
Reaction equation
[CH3:1][N:2]([CH2:4][CH2:5][OH:6])[CH3:3].[C:7](=O)([O:10][CH:11]([CH3:13])[CH3:12])[O:8]C>CO>[C:7](=[O:8])([O:6][CH2:5][CH2:4][N:2]([CH3:3])[CH3:1])[O:10][CH:11]([CH3:13])[CH3:12]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
reacting 2-(N,N-dimethylamino)ethanol with the methyl isopropyl carbonate formed in step i) in the presence of a transesterification catalyst to form isopropyl 2-dimethylaminoethyl carbonate and methanol, under such conditions that the 2-(N,N-dimethylamino)ethanol also reacts with the di-isopropyl carbonate formed in step i) to form more isopropyl 2-dimethylaminoethyl carbonate,
Sources & evidence
- ORD record
- ord-f269e07499c340eda1dc798f93b250ba
- Source dataset
- uspto-grants-1996_10
- Patent number
- US05563288
Reaction notes
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