3,5-Dimethyl-4-hydroxybenzonitrile → 4-(2-Methyl-2H-tetrazol-5-yl)phenol

HRID 865685

Reaction equation

[CH3:1][N:2]1[N:6]=[N:5][C:4]([C:7]2[CH:12]=[C:11](C)[C:10]([OH:14])=[C:9](C)[CH:8]=2)=[N:3]1.CC1C=C(C#N)C=C(C)C=1O>>[CH3:1][N:2]1[N:6]=[N:5][C:4]([C:7]2[CH:12]=[CH:11][C:10]([OH:14])=[CH:9][CH:8]=2)=[N:3]1

Participants

Reactant 2

HCID 201763,5-Dimethyl-4-hydroxybenzonitrile

HCID 148372Win 58768

Product 1

HCID 1356489564-(2-Methyl-2H-tetrazol-5-yl)phenol

Procedure

Preparation of 2-methyl-5-(3,5-dimethyl-4-hydroxyphenyl)tetrazole was prepared by the procedure described above for Intermediate 5 starting with 2,6-dimethyl-4-cyanophenol.

Workup

customwas prepared by the procedure

Sources & evidence

ORD record: ord-c9b85156842a48e3a64d4ea9df67465e
Source dataset: uspto-grants-1996_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05567717

Linked notes

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