HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylpiperazine → 1-[4-[(2,3-Dihydro-2-oxo-1H-imidazo[4,5-b]quinolin-7-yl)oxy]-1-oxobutyl]-4-phenylpiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylpiperazine | HCID 7096 | — |
| Reactant | 4-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-butyric acid | HCID 14280990 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-[4-[(2,3-Dihydro-2-oxo-1H-imidazo[4,5-b]quinolin-7-yl)oxy]-1-oxobutyl]-4-phenylpiperazine | HCID 14281014 | — |
Reaction Steps
This compound, m.p. 277°-279° C., obtained as a dimethylformamide solvate was prepared analogous to Example 15 from 4-[(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]quinolin-7-yl)oxy]butyric acid and 4-phenylpiperazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04775674 |
| Source dataset | uspto-grants-1988_10 |
| ORD ID | ord-37505811246b44189916e9d752ec610d |
| Source note | uspto-grants-1988_10 |