Sodium Hydroxide → inositol 1,2,6-triphosphate

HRID 867855

Reaction equation

HRID 867855 reaction equation
[CH:1]1([O:32][P:33]([O-:36])([O-:35])=[O:34])[CH:6]([O:7][P:8]([O-:11])([O-:10])=[O:9])[CH:5]([O:12][P:13]([O-:16])([O-:15])=[O:14])[CH:4]([O:17]P([O-])([O-])=O)[CH:3]([O:22]P([O-])([O-])=O)[CH:2]1[O:27]P([O-])([O-])=O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[OH-].[Na+]>C(O)C>[C@H:4]1([OH:17])[CH:3]([OH:22])[C@@H:2]([OH:27])[C@@H:1]([O:32][P:33]([OH:36])([OH:35])=[O:34])[CH:6]([O:7][P:8]([OH:10])([OH:11])=[O:9])[C@@H:5]1[O:12][P:13]([OH:15])([OH:16])=[O:14]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 66391Phytate Persodium

Product 1

HCID 65762inositol 1,2,6-triphosphate

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

100 ml of the fraction containing D-myo-inositol-1.2.6-triphosphate obtained in Example 15 was neutralized to a pH of about 7 with an aqueous solution of NaOH. After addition of 100 ml ethanol the volume of the solution was reduced by evaporation and the sodiumsalt was precipitated, centrifuged, recrystallized and dried in vacuum. The purified sodiumsalt of D-myo-inositol-1.2.6-triphosphate obtained was structurally confirmed by analysis with H-NMR.

Workup

  1. customwas reduced by evaporation
  2. customthe sodiumsalt was precipitated
  3. customrecrystallized
  4. customdried in vacuum

Sources & evidence

ORD record
ord-9f33052edcde4fbab35e0f7266edce33
Source dataset
uspto-grants-1988_10
Patent number
US04777134

Linked notes

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