Semicarbazide hydrochloride → HCID 178457375, compound
Reaction equation
[CH:1]([NH:4][CH2:5][CH2:6][N:7]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:10](=O)[C:8]1=[O:9])([CH3:3])[CH3:2].Cl.[NH2:19][NH:20][C:21]([NH2:23])=[O:22]>>[CH:1]([NH:4][CH2:5][CH2:6][N:7]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)/[C:10](=[N:19]\[NH:20][C:21]([NH2:23])=[O:22])/[C:8]1=[O:9])([CH3:3])[CH3:2]Participants
3
Procedure
By using 1-(2-isopropylaminoethyl)isatin and semicarbazide hydrochloride, a method analogous to that described in Example 10 was carried out, and the reaction product was recrystallized from ethanol to obtain (E)-1-(2-isopropylaminoethyl)isatin 3-semicarbazone having a melting point of 169°-172° C. (decomposition) (yield: 49.8%).
Workup
- customthe reaction product was recrystallized from ethanol
Sources & evidence
- ORD record
- ord-ec806857fa414720b0039066eb587a42