2-Bromotoluene → 7-(o-Tolyl)-N-(4-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-amine
Reaction equation
[Br:1][c:2]1[c:3]([CH3:8])[cH:4][cH:5][cH:6][cH:7]1.[C:9](=[O:10])([O-:11])[O-:12].[Cs+:13].[Cs+:14].[F:15][C:16]([c:17]1[cH:18][cH:19][c:20]([NH:23][c:24]2[c:25]3[c:26]([n:27][cH:28][n:29]2)[CH2:30][NH:31][CH2:32][CH2:33]3)[cH:21][cH:22]1)([F:34])[F:35].[O:36]1[CH2:37][CH2:38][O:39][CH2:40][CH2:41]1>>[c:2]1([N:31]2[CH2:30][c:26]3[c:25]([c:24]([NH:23][c:20]4[cH:19][cH:18][c:17]([C:16]([F:15])([F:34])[F:35])[cH:22][cH:21]4)[n:29][cH:28][n:27]3)[CH2:33][CH2:32]2)[c:3]([CH3:8])[cH:4][cH:5][cH:6][cH:7]1
