HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → (2,4-Difluoro-benzyl)-[3-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-propyl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,4-Difluorobenzylamine | HCID 2733244 | — |
| Reactant | 3-[3-(3-Bromo-propoxy)phenyl]-thieno[2,3-d]isoxazole | HCID 21983559 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | (2,4-Difluoro-benzyl)-[3-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-propyl]-amine | HCID 21983598 | — |
Reaction Steps
The title compound is prepared from 3-[3-(3-bromo-propoxy)-phenyl]-thieno[2,3-d]isoxazole, potassium carbonate, 2,4-difluorobenzylamine, and acetonitrile essentially as described above in example 56. Purity by LC/MS (APCI)=95%, [M+H]+=401.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091199B1 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-54b7f7e31bf245bfadb9639c6db33c29 |
| Source note | uspto-grants-2006_08 |