3-Chloro-benzofuro[3,2-c]isoquinoline-5-ol → 5,8-Dichlorobenzofuro[3,2-c]isoquinoline
Reaction equation
O[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]2[O:12][C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[C:4]=2[N:3]=1.[Cl:20]C1C=C2C(C3OC4C=CC=CC=4C=3N=C2O)=CC=1>>[Cl:20][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]2[O:12][C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[C:4]=2[N:3]=1Participants
3
Procedure
The procedure was similar to step S19C, while the starting material was 24B in stead of 19B.
Sources & evidence
- ORD record
- ord-b75646df2d5642698cf96a07be7c32c7
- Source dataset
- uspto-grants-2015_03
- Patent number
- US08969373B2
Reaction notes
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