HCID 178487264, compound → 3-Methoxy-5-chloro-benzofuro[3,2-c]isoquinoline

Reaction equation

O[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH3:13])[CH:10]=2)[C:5]2[O:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[C:4]=2[N:3]=1.[Cl:21]C1C=C2C(C3OC4C=CC=CC=4C=3N=C2O)=CC=1>>[CH3:13][O:12][C:9]1[CH:10]=[C:11]2[C:6]([C:5]3[O:14][C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=4[C:4]=3[N:3]=[C:2]2[Cl:21])=[CH:7][CH:8]=1

Participants

Reactant 2

HCID 178487264HCID 178487264, compound

HCID 1785169623-Chloro-benzofuro[3,2-c]isoquinoline-5-ol

Product 1

HCID 867222793-Methoxy-5-chloro-benzofuro[3,2-c]isoquinoline

Procedure

The procedure was similar to step S19C, while the starting material was 25B in stead of 19B.

Sources & evidence

ORD record: ord-8a41539d21d84c1e809dbb7c69ef0cbf
Source dataset: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08969373B2

Reaction notes

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