Pyrimidin-5-ol → 5-Formyl-2-(pyrimidin-5-yloxy)benzonitrile
Reaction equation
F[C:2]1[CH:9]=[CH:8][C:7]([CH:10]=[O:11])=[CH:6][C:3]=1[C:4]#[N:5].[N:12]1[CH:17]=[C:16]([OH:18])[CH:15]=[N:14][CH:13]=1>>[CH:10]([C:7]1[CH:8]=[CH:9][C:2]([O:18][C:16]2[CH:17]=[N:12][CH:13]=[N:14][CH:15]=2)=[C:3]([CH:6]=1)[C:4]#[N:5])=[O:11]Participants
3
Procedure
The title compound was prepared by a procedure similar to that described for D4 starting from 2-fluoro-5-formylbenzonitrile and pyrimidin-5-ol.
Sources & evidence
- ORD record
- ord-95839484d79d42b881fd5a69c4f2da75
- Source dataset
- uspto-grants-2015_03
- Patent number
- US08975400B2
Reaction notes
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