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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 873101Generated: October 27, 2026

3-Chloro-5-hydroxybenzotrifluoride → 6-(3-Chloro-5-(trifluoromethyl)phenoxy)nicotinaldehyde

https://huagongshe.com/reaction/873101

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-5-hydroxybenzotrifluorideHCID 3852718—
Reactant2-Fluoro-5-formylpyridineHCID 16414246—
Product6-(3-Chloro-5-(trifluoromethyl)phenoxy)nicotinaldehydeHCID 86724177—

Reaction Steps

The title compound was prepared by a procedure similar to that described for D4 starting from 6-fluoronicotinaldehyde and 3-chloro-5-(trifluoromethyl) phenol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08975400B2
Source datasetuspto-grants-2015_03
ORD IDord-34f5c86775f44d378e7362776c78c26f
Source noteuspto-grants-2015_03