3-(Trifluoromethyl)benzylamine → 2-[3-Trifluoromethylbenzylamino]-4-[benzimidazol-1-yl]pyrimidine

HRID 87391

Reaction equation

HRID 87391 reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[n:6][cH:7][cH:8][c:9](-[n:11]2[cH:12][n:13][c:14]3[c:15]2[cH:16][cH:17][cH:18][cH:19]3)[n:10]1.[F:20][C:21]([c:22]1[cH:23][c:24]([CH2:25][NH2:26])[cH:27][cH:28][cH:29]1)([F:30])[F:31]>>[c:5]1([NH:26][CH2:25][c:24]2[cH:23][c:22]([C:21]([F:20])([F:30])[F:31])[cH:29][cH:28][cH:27]2)[n:6][cH:7][cH:8][c:9](-[n:11]2[cH:12][n:13][c:14]3[c:15]2[cH:16][cH:17][cH:18][cH:19]3)[n:10]1

Participants

3

Reactant 2

HCID 759623-(Trifluoromethyl)benzylamineHCID 155496402-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine

Product 1

HCID 183756192-[3-Trifluoromethylbenzylamino]-4-[benzimidazol-1-yl]pyrimidine

Sources & evidence

ORD record
ord-7dcb930169154a1f971fd8a93abc4542
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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