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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 874Generated: October 25, 2026

tert-butyl N-(azetidin-3-ylmethyl)carbamate → 3-(N-Boc)-(2-aminoethyl)azetidine

https://huagongshe.com/reaction/874

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl N-(azetidin-3-ylmethyl)carbamateHCID 15346872—
Reactant3-(N-tert-butyloxycarbonylaminoethyl)-1-benzhydryl azetidineHCID 54181727—
Product3-(N-Boc)-(2-aminoethyl)azetidineHCID 37818431—

Reaction Steps

The title compound was prepared from 3-(N-tert-butyloxycarbonylaminoethyl)-1-benzhydryl azetidine according the procedure for 3-(N-tert-butyloxycarbonylaminomethyl) azetidine, in a yield of 1.2 g (70%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05723444
Source datasetuspto-grants-1998_03
ORD IDord-b116e8105ba1433db653190ba3814a43
Source noteuspto-grants-1998_03