2,4,6-Trichlorobenzoyl chloride → N-[3-(2,4,6-trichlorobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]cyclopropanecarboxamide
Reaction equation
[NH:1]1[C:5]2=[CH:6][N:7]=[C:8]([NH:10][C:11]([CH:13]3[CH2:15][CH2:14]3)=[O:12])[CH:9]=[C:4]2[CH:3]=[CH:2]1.[Cl:16][C:17]1[CH:25]=[C:24]([Cl:26])[CH:23]=[C:22]([Cl:27])[C:18]=1[C:19](Cl)=[O:20]>>[Cl:16][C:17]1[CH:25]=[C:24]([Cl:26])[CH:23]=[C:22]([Cl:27])[C:18]=1[C:19]([C:3]1[C:4]2[C:9](=[C:8]([NH:10][C:11]([CH:13]3[CH2:15][CH2:14]3)=[O:12])[N:7]=[CH:6][CH:5]=2)[NH:1][CH:2]=1)=[O:20]Participants
3
Procedure
N-[3-(2,4,6-Trichlorobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]cyclopropanecarboxamide (Compound No. 45) was prepared using N-(1H-pyrrolo[2,3-c]pyridin-5-yl)cyclopropane carboxamide and 2,4,6-trichlorobenzoyl chloride.
Sources & evidence
- ORD record
- ord-ea6ba605925e423d96163a1b55135ee8
- Source dataset
- uspto-grants-2015_03