Methyl benzo[d]thiazole-6-carboxylate → 6-(Aminomethyl)benzothiazole

HRID 876804

Reaction equation

HRID 876804 reaction equation
[S:1]1[C:5]2[CH:6]=[C:7]([C:10](OC)=O)[CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.Cl.S1C2C=C[N:20]=CC=2C=C1CN>>[S:1]1[C:5]2[CH:6]=[C:7]([CH2:10][NH2:20])[CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 595763Methyl benzo[d]thiazole-6-carboxylateHCID 67306703Thieno[3,2-c]pyridin-2-ylmethanamine hydrochloride

Product 1

HCID 450770136-(Aminomethyl)benzothiazole

Procedure

Intermediate T was prepared from methyl benzo[d]thiazole-6-carboxylate (T-2) following similar procedures for synthesizing intermediate D from D-2, as described above. MS (m/z): 165 (M+1)+.

Sources & evidence

ORD record
ord-edf431f47a4543738654c68fb67a65e4
Source dataset
uspto-grants-2015_03
Patent number
US08987269B2

Linked notes

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